Photoprotection and the Science Behind Skin Healing

[摘要] In the first of two sessions from the 31 st European Academy of Dermatology and Venereology (EADV) Congress, Thierry Passeron, University of Nice Sophia Antipolis, France, presented a large international survey that showed that while people are aware of the dangers of sun exposure, many still seek to tan and do not use or may not understand protective measures. In the second half of this session, Susana Puig, University of Barcelona, Spain, discussed data on the use of a high factor, broad-spectrum sunscreen combined with nicotinamide and panthenol. In people with photodamaged skin, the cream was shown to downregulate genes involved in apoptosis, the immune system, and cancer and upregulate collagen genes. In people with actinic keratosis (AK) and its precursor, field cancerisation (FC), treatment led to downregulation of genes involved in a number of signalling pathways, including those implicated in cancer, the cell cycle, and apoptosis. In the second session, Jean-Michel Amici, Université Bordeaux, France, discussed the wound healing process and the role of the immune system and skin microbiome. Delphine Kerob, La Roche-Posay Laboratoires, Paris, France, then presented data from a survey of people with scars that revealed how redness, itching, pain, and burning could persist for at least a year in some people, and skin discomfort can impact quality of life (QoL). Kerob also presented findings from recent studies of effects of the cream Cicaplast Baume B5+® (La Roche-Posay, L’Oréal UK Ltd, London, UK). Cicaplast Baume B5+, which contains a prebiotic complex as well as panthenol, madecassoside, and moisturisers, showed positive effects on skin healing following laser treatment for skin damage.

[学科分类] 公共、环境与职业健康