Superficial cerebellar microbleeds and siderosis associated with meningeal carcinomatosis

[摘要] Meningeal carcinomatosis (MC), also known ascarcinomatous meningitis or leptomeningeal metastasis, isan unusual phenomenon characterized by the metastasis ofcancer cells to the leptomeninges. The incidence of MC inpatients with solid tumors is 5–8% and that in patients withhematologic malignancies is 5–15% (1). Early diagnosisand timely treatment of MC are crucial for improvingthe prognosis of patients. However, the early-stagediagnosis of MC remains challenging, with nonspecificpresenting symptoms and insufficient sensitivity of auxiliaryexaminations. Contrast magnetic resonance imaging (MRI)is very suggestive in the diagnosis of MC, which showsirregular or nodular leptomeningeal or dural enhancement.In contrast, traditional MRI sequences of patients with MCoften have no specific brain lesions (2). Here, we describea case of superficial cerebellar microbleeds and siderosisassociated with MC. To our knowledge, there have been nopublished reports about susceptibility-weighted imaging(SWI) findings of MC.

[学科分类] 外科医学