Images of giant cell tumor and chondroblastoma around the knee: retrospective analysis of 99 cases

[摘要] Background: It is difficult to differentiate giant cell tumors of the bone (GCTB) from chondroblastoma around the knee based on imaging findings. This study analyzed the imaging features of these 2 diseases for better differentiation. Methods: This retrospective cross-sectional cohort study reviewed data of patients with pathologically confirmed GCTB (n=81; age 15–75 years; median age 33 years) and chondroblastoma (n=18; age 12–34 years; median age 14 years). In all, 18 imaging signs were analyzed. Results: Patients with chondroblastoma were relatively younger than those with GCTB. On imaging, lesion length was significantly (P<0.00001) smaller in chondroblastoma [range, 15.80–78.30 mm; mean ± standard deviation (SD) 34.15±18.24 mm; 95% confidence interval (CI): 24.05–44.25 mm] than in GCTB [range, 30.10–117.50 mm; mean ± SD 59.73±15.28 mm; 95% CI: 56.24–63.22 mm]. Significantly more (P<0.05) chondroblastoma lesions had calcification (76.5% vs. 1.3%), lobulation (77.8% vs.15 mm (84.6% vs. 41.1%) than did GCTB lesions, whereas significantly more (P<0.05) GCTB lesions were greater than half the host bone diameter (74.1% vs. 16.7%) and had a lesion long axis that was consistent with that of the host bone (98.8% vs.0.05) between the 2 tumors in the remaining 11 imaging signs. Conclusions: 15 mm are parameters that can be used to differentiate GCTB from chondroblastoma around the knee.

[学科分类] 外科医学

[关键词] Bone;chondroblastoma;giant cell tumor;imaging;knee