Around the time of a hip fracture, older East Asian female patients tend to measure lower densitometric femoral neck and total hip T-scores than older Caucasian female patients: a literature analysis

[摘要] The clinical significance of osteoporosis lies in thefractures that occur, and the most important fracture is hipfracture. According to the 1994 World Health Organization(WHO) criteria, the T-score is defined as: (BMDpatient–BMDyoung normal mean)/SDyoung normal population, where BMD is bonemineral density and SD is the standard deviation. When thefemoral neck is measured in adult women, a cutpoint valueof patient BMD of 2.5 SD below the BMDyoung normal meansatisfies that the prevalence of osteoporosis for those aged≥50 years is about 16.2%, the same as the lifetime riskof hip fragility fracture (FF) (1,2). If other sites are alsoconsidered, this cutpoint value identifies approximately 30%of postmenopausal women as having osteoporosis, whichis approximately equivalent to the lifetime risk of FF at thespine, hip, or forearm. The FF prevalence of older Chinesewomen is slightly less than half that of Caucasians (3,4).This is the case for hip FF (5-7), radiographic vertebralFF (8), clinical vertebral FF (9-11), and many other FFsites (3,4,12,13). As compared with Caucasians, Chinesedemonstrate an overall stronger skeleton property (14).

[学科分类] 外科医学

[关键词] Bone mineral density;osteoporosis;diagnostic criteria;Chinese women;prevalence