The future in an RNA molecule: from mRNA vaccines to therapeutics – An interview with Drew Weissman

[摘要] The COVID-19 pandemic created an unprecedentedstate of emergency, during which medical doctorsstruggled to save lives, and scientists worked feverishly to study the virus, identify effective drugs ordevelop vaccines in record time. Several differentapproaches to vaccine production were used, some ofwhich were traditional and others quite innovative.mRNA vaccines had never been licensed for humansbefore, but the remarkable results of the SARS-CoV2 vaccines produced by Pfizer/BioNTech and Moderna rapidly dissolved all scepticism. The simplicity ofits nature, the potent immunity it provides, and itssafety, turned the mRNA vaccine into the mostwidely distributed type of vaccine during the pandemic.