Hemophagocytosis by acute myeloid leukemia blasts associated to poor clinical outcomes

[摘要] A 74-year-old man was referred to the university hospital for fatigue,weight loss, and thrombocytopenia. Initial examination revealed maculopapular lesions on his body.Subsequent blood tests showed mild normocytic anemia (12.1 g/dL),thrombocytopenia (43 × 109/L), and 3% blast cells among leukocytes(14.17 × 109/L). Coagulation assessment found disseminated intravascular coagulation (DIC). Biopsy of cutaneous maculopapular lesionsfound a perivascular infiltration by blast cells in the dermis, diagnosingleukemia cutis.

[关键词] Acute Myeloid Leukemia;AML;Hemophagocytosis