Atypical cytologic mantle cell lymphoma presentation

[摘要] A 61-year-old patient presents with monoclonal B lymphocytosis diagnosed in 2014 with initial moderate splenic involvement without anyclinical symptoms.In 2021, during a follow-up workup, a Positron Emission Tomography scan is performed objectifying homogeneous splenic involvementwith moderate colonic hypermetabolism.Cytology showed a monoclonal lymphocytosis composed of smalllymphocytes with mature chromatin and high nucleocytoplasmic ratioregularly displaying small cytoplasmic expansions (A: May-GrunwaldGiemsa stain, 50× objective, B: May-Grunwald-Giemsa stain, 100×objective).