Formulation and Evaluation of Semi Solid Dosage Forms Based On Naturally Occurring Analgesic Agent Camphor

[摘要] Oral analgesics are commonly prescribed for the treatment of acute and chronic pain, but these agents often produce adverse systemic effects, which some times are severe ,so topical administration of analgesics is an alternative method. The aim of present work is to develop semi solid preparations of natural analgesics like camphor. Three different strengths were prepared which are 25mg,50mg,100mg in two different bases that are hydrophilic and hydrophobic. All the prepared formulations were evaluated for PH, spreadability, diffusion studies. The selected formulations were evaluated for in-vivo studies in comparison with marketed preparations .The finalized preparation was kept for stability studies according to ICH guidelines.

[学科分类] 药学

[关键词] Pain;Camphor;Ointment.