Evaluation of Blood and CSF Isolated Bacteria and Their Antimicrobial Resistance in Hospitalized Patients in Ahvaz Golestan Hospital in 2020

[摘要] Background and Objectives: Infection of the blood and cerebrospinal fluid can have irreparable consequences and even death. In the present study, the prevalence of bacteria causing blood and cerebrospinal fluid infection and their antibiotic resistance in hospitalized patients was investigated.Subjects and Methods: In this present descriptive-cross-sectional study, the results of all blood and cerebrospinal fluid samples were sent for culture from the hospitalized patients of Golestan Hospital in Ahvaz in the first six months of 2019 were examined. Relevant information was extracted from patients’ medical records.Results: In this study, 12.17% of blood culture were positive and 7.6% of cerebrospinal fluid culture were positive. The most common bacteria causing blood infections were Staphylococcus Coagulase Negative (32.5%), Klebsiella (24.1%) and Pseudomonas (21.7%), and the most common bacteria causing cerebrospinal fluid infection were Klebsiella (30.9%), Streptococcus. group D (Enterococcus) (20.6%) and pseudomonas (15.5%). The highest bacterial resistance was observed for Ampicillin, Ceftriaxone, Cefazolin, Cefixime and Cefotaxime antibiotics, and the highest sensitivity was observed for Meropenem, Colistin, and Levofloxacin antibiotics.Conclusion: Since the bacterial resistance pattern is always changing, it is suggested that before starting any empirical treatment in infectious diseases, sensitive antibiotics for common bacterial agents are recommended for a more efficient treatment.

[学科分类] 基础医学

[关键词] Blood infection;cerebrospinal fluid;Bacteria;Antibiotic Resistance