Therapeutic strategies for allergic diseases

[摘要] Many drugs are now in development for the treatment of atopic diseases, including asthma, allergic rhinitis and atopic dermatitis. These treatments are based on improvements in existing therapies or on a better understanding of the cellular and molecular mechanisms involved in atopic diseases. Although most attention has been focused on asthma, treatments that inhibit the atonic disease process would have application to all atonic diseases, as they often coincide. Most of the many new therapies in development are aimed at inhibiting components of the allergic inflammatory response, but in the future there are real possibilities for the development of preventative and even curative treatments.

[关键词] INDUCED AIRWAY HYPERRESPONSIVENESS;COLONY-STIMULATING FACTOR;CHRONIC SEVERE ASTHMA;ANTI-IGE ANTIBODY;TRANSCRIPTION FACTOR;MONOCLONAL-ANTIBODY;INTERFERON-GAMMA;CYTOKINE EXPRESSION;HUMAN EOSINOPHILS;T-LYMPHOCYTES