Absence of proximal muscle weakness, dysarthria, and facial diplegia suggests Guillain–Barre syndrome rather than CIDP

[摘要] The aim of this letter to the editor is to discuss the etiology and pathophysiology of chronic inflammatory demyelinating polyneuropathy (CIDP) in two patients, of whom one experienced a mildly symptomatic SARS-CoV-2 infection 2 months prior to onset of the CIDP (patient-1), whereas patient-2 developed CIDP with bilateral facial palsy 19 days after receiving a shot of an RNA-based anti-SARS-CoV-2 vaccine. Causality between the SARS-CoV-2 infection and CIDP in patient-1 remains unsupported and the diagnosis CIDP in patient-2 remains questionable. Although delineation between CIDP and GBS is not clear cut, bilateral facial palsy and absence of proximal involvement suggest GBS rather than CIDP.

[发布日期] 2022-12-02

[关键词] SARS-CoV-2;COVID-19;Vaccination;CIDP;Guillain–Barre syndrome