DE-FG02-04ER63746 FinalTechnicalReport

[摘要] This is the final technical report for a project involving the study of stress response systems in the radiation-resistant bacterium, Deinococcus radiodurans. Three stresses of importance for a mixed waste treatment strain were studied, heat shock, solvent shock, and phosphate starvation. In each case, specific genes involved in the ability to survive the stress were identified using a systems biology approach, and analysis of mutants was used to understand mechanisms. This study has led to increased understanding of the ways in which a potential treatment strain could be manipulated to survive multiple stresses for treatment of mixed wastes.

[发布日期] 2009-09-05

[学科分类] 生物科学（综合）

[关键词] BIOLOGY;FASTING;GENES;MUTANTS;PHOSPHATES;SOLVENTS;STRAINS;STRESSES;WASTE PROCESSING;WASTES Deinococcus;stress response;environmental remediation