Dietary consumption, fluid consumption and risk of developing bladder cancer

[摘要] This thesis focuses on three different parts: (1) An analyses of dietary consumption, diet diversity and risk of developing bladder cancer within a case-control study in China. This study showed that higher diet diversity, particularly a diet varied in fruit may reduce the risk of developing bladder cancer. In addition, there was a positive association between the consumption of red meat, organ meat, leafy vegetables, bulb vegetables or preserved vegetables may increase the risk of bladder cancer. The consumption of citrus fruits, stone fruits, vine fruits, flower vegetables, fresh fish, potatoes and dairy products may decrease the risk of developing bladder cancer. (2) A dose-response meta-analysis on the association between total fluid consumption and bladder cancer was conducted. The results of this study suggest a non-linear relationship between total fluid intake and bladder cancer risk in men.Also, the findings indicates that low to moderate fluid consumption was not associated with an increased risk of developing bladder cancer; although fluid consumption exceeding 8 cups per day might increase the risk of developing bladder cancer. (3) A pooled analysis on fluid consumption and risk of developing bladder cancer using individual patient data from the Bladder Cancer Epidemiology and Nutritional Determinant consortium. The results suggest that excess consumption of coffee per day may increase the risk of developing bladder cancer in men.

[发布机构] University:University of Birmingham;Department:School of Health and Population Sciences

[关键词] R Medicine;RA Public aspects of medicine;RA0421 Public health. Hygiene. Preventive Medicine