Detection heart failures (HF) biomarkers by proton transfer reaction - mass spectrometry and ion mobility spectrometry

[摘要] Exhaled breath contains 1% of volatile organic compounds. The concentration of individual biomarkers in hundreds of volatile organic compounds lies within the range ppm- ppb. In compare with control group the concentrations of acetone, acetic acid, ethanol, propylene biomarkers is significantly higher in HF-PEF group.

[发布机构] National Research Nuclear University, MEPhI (Moscow Engineering Physics Institute), Kashirskoe shosse 31, Moscow; 115409, Russia^1;I.M. Sechenov First Moscow State Medical University, Trubetskaya st. 8-2, Moscow; 119991, Russia^2;A.M.Obukhov Institute of Atmospheric Physics RAS, Pyzhevskii pereulok 3, Moscow; 119017, Russia^3

[关键词] Control groups;Exhaled breaths;Heart failure;Ion mobility spectrometry;Proton-transfer reaction mass spectrometries