Evaluation of antibacterial, antioxidant and GC-MS analysis of ethanolic seed extract of Myristica dactyloides

[摘要] In this present investigation we analysed the antimicrobial and antioxidant activities of ethanol extract of Myristica dactyloides. The antimicrobial activity of the ethanol extract was evaluated by the agar well diffusion method against of E. coli, Klebsiella pneumonia, Streptococcus sp, and Staphylococcus aureus at different concentrations. The antibacterial activity showed the result in a dose-dependent manner. The free radical scavenging was evaluated against DPPH, hydroxyl, and nitric oxide radicals. In DPPH, hydroxyl and nitric oxide scavenging assay showed the IC 50 value of the extract was found to be 20 μg/ml, 48.25 and 30 μg/ml, respectively. The plant can be considered as promising antioxidant properties with high potential value for drug development for various diseases.

[发布机构] PG and Research Department of Biochemistry, Adhiparasakthi College of Arts and Science, Kalavai, Vellore District; 632506, India^1;School of Bio-Sciences and Technology, VIT University, Vellore; 632014, India^2

[效力级别] 工业技术

[关键词] Anti-bacterial activity;Anti-microbial activity;Antimicrobial and antioxidant activities;Antioxidant properties;Dose-dependent manner;Free radical scavenging;Myristica dactyloides;Staphylococcus aureus