Absolute measurement of low energy electron-induced strand-break damage in films of plasmid DNA and plasmid DNA/Dap2+ complexes

[摘要] A simple model of electron transmission in thin film targets permits absolute measurement of cross section for electron-induced damage in such films of DNA and DNA complexed with 1-3 diaminopropane.

[发布机构] Laboratoire de Chimie Physique et Rayonnements - Alain Chambaudet, LRC CEA, Université de Franche-Comté, 16 route de Gray, Besançon cedex; F-25030, France^1;Départment de Médecine Nucléaire et Radiobiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke; QC; J1H 5N4, Canada^2;Research Institute of Photocatalysis, State Key Laboratory, Fuzhou University, Fuzhou; 350002, China^3

[关键词] Absolute measurements;Diaminopropane;Electron transmission;Induced damage;Low energy electrons;Plasmid DNA;Simple modeling;Strand breaks