The effect of time in the exposure of theobromine gel to enamel and surface hardness after demineralization with 1% citric acid

[摘要] Theobromine is one of the alkaloid compounds that can be found in cacao (Theobroma cacao). It is said that theobromine can prevent enamel demineralization. The aim of this research was to evaluate the effect of different exposure times to 200 mg/L theobromine gel on enamel microhardness after demineralization in 1% citric acid. Twenty-eight specimens of human premolar teeth were divided into four groups and were immersed in 1% citric acid (pH 4) for 2.5 minutes. Then 200 mg/L theobromine gel was exposed to the specimens for 16 minutes (n = 7), 48 minutes (n = 7), and 96 minutes (n = 7). Enamel microhardness (KHN) values were tested using the Knoop Microhardness Tester (Shimadzu, Japan) using a 50-gram load for 5 seconds. A statistical test was performed using the Friedman test, Wilcoxon test, Kruskal-Wallis test, and Mann-Whitney test. The results showed a significant decrease, of microhardness values after demineralization with 1% citric acid. There was also a significant increase in hardness (p

[发布机构] Department of Dental Materials, Faculty of Dentistry, Universitas Indonesia, Indonesia^1

[效力级别] 医药卫生 [学科分类] 卫生学

[关键词] Alkaloid compounds;Effect of time;Enamel demineralization;Enamel microhardness;Knoop microhardness;Kruskal-Wallis tests;Surface hardness;Theobroma cacao