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Tetrazolium salt monomers for gel dosimetry II: Dosimetric characterization of the ClearView? 3D dosimeter
[摘要] ClearView is a colourless radiochromic 3D dosimeter that is chemically and mechanically stable before and after irradiation. Upon irradiation, colour is generated from the radiochemical reduction of a tetrazolium salt suspended within a gellan gum gel. Here we present the dosimetric characterization of small and large volume samples (4 mL and 1 L, respectively) from three different batches of ClearView. The dose sensitivity was linear up to 80 Gy and constant within a batch but varied among batches between 3.4×10-3and 4.1×10-3Gy-1cm-1. Once generated, the radiation signal within the large samples remained unchanged for at least 58 days. Both electrons and photons produced the same signal at different energy levels; however, at dose rates below 400 cGy/min, a drop in sensitivity was observed. Overall, ClearView is best suited for relative dosimetry up to 80 Gy at high dose rates.
[发布日期]  [发布机构] Modus Medical Devices Inc., 1570 N Routledge Park, London; ON; N6H 5L6, Canada^1;Department of Chemical and Biochemical Engineering, University of Western Ontario, London; ON; N5A 5B9, Canada^2;Biomedical Engineering Program, University of Western Ontario, London; ON; N6A 5B9, Canada^3
[效力级别]  [学科分类] 
[关键词] 3d dosimeters;Dose sensitivity;Gel dosimetry;Gellan gum;High dose rate;Large volumes;Mechanically stable;Radiation signals [时效性] 
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