Shielding of Sensitive Electronic Devices in Magnetic Nanoparticle Hyperthermia Using Arrays of Coils

[摘要] In Magnetic Nanoparticle Hyperthermia (MNH) an externally applied electromagnetic field transfers energy to the magnetic nanoparticles in the body, which in turn convert this energy into heat, thus locally heating the tissue they are located in. This external electromagnetic field is sufficiently strong so as to cause interference and affect sensitive electronic equipment. Standard shielding of magnetic fields involves Faraday cages or coating with high-permeability shielding alloys; however, these techniques cannot be used with optically sensitive devices, such as those employed in Optical Coherence Tomography or radionuclide imaging. In this work we present a method to achieve magnetic shielding using an array of coils. The magnetic field generated by a single coil was calculated using the COMSOL physics simulation toolkit. Software was written in C/C++ to import the single-coil data, and then calculate the positions, number of turns and currents in the shielding coils in order to minimize the magnetic field strength at the desired location. Simulations and calculations have shown that just two shielding coils can reduce the magnetic field by 2-3 orders of magnitude.

[发布机构] Department of Biomedical Engineering, Technological Educational Institute of Athens, Athens, Greece^1

[效力级别] 医药卫生 [学科分类] 卫生学

[关键词] External electromagnetic field;Magnetic field strengths;Magnetic nano-particles;Orders of magnitude;Physics simulation;Radionuclide imaging;Sensitive electronic devices;Sensitive electronic equipment