3-D localization of gamma ray sources with coded apertures for medical applications

[摘要] Several small gamma cameras for radioguided surgery using CdTe or CdZnTe have parallel or pinhole collimators. Coded aperture imaging is a well-known method for gamma ray source directional identification, applied in astrophysics mainly. The increase in efficiency due to the substitution of the collimators by the coded masks renders the method attractive for gamma probes used in radioguided surgery. We have constructed and operationally verified a setup consisting of two CdTe gamma cameras with Modified Uniform Redundant Array (MURA) coded aperture masks of rank 7 and 19 and a video camera. The 3-D position of point-like radioactive sources is estimated via triangulation using decoded images acquired by the gamma cameras. We have also developed code for both fast and detailed simulations and we have verified the agreement between experimental results and simulations. In this paper we present a simulation study for the spatial localization of two point sources using coded aperture masks with rank 7 and 19.

[发布机构] Greek Atomic Energy Commission, Greece^1;Technological Educational Institute of Sterea Ellada, Greece^2;Hellenic Army Academy, Greece^3

[效力级别] 医药卫生 [学科分类] 卫生学

[关键词] Coded aperture imaging;Coded aperture masks;Directional identifications;Pinhole collimators;Radioactive sources;Radioguided surgery;Simulation studies;Spatial localization