An evaluation of the clinical potential of tissue diffraction studies

[摘要] Medical imaging is a long established part of patient management in the treatment of disease. However, in most cases it only provides anatomical detail and does not provide any form of tissue characterisation. This is particularly true for X-ray imaging. Recent studies on tissue diffraction have shown that true molecular signatures can be derived for different tissue types. Breast cancer samples and liver tissue have been studied. It has been shown that diffraction profiles can be traced away from the primary tumour in excised breast tissue samples and that potentially 3mm fat nodules in liver tissue can be identified in patients at acceptable doses.

[发布机构] Department of Medical Physics and Biomedical Engineering, UCL, London; WC1E 6BT, United Kingdom^1;Diagnostic Radiology and Radiation Protection, Christie Medical Physics and Engineering, Christie NHS Foundation Trust, Manchester; M20 4BX, United Kingdom^2;Institute of Biomedical Engineering, UCL, London; WC1E 6BT, United Kingdom^3

[效力级别] 医药卫生 [学科分类] 卫生学

[关键词] Breast Cancer;Breast tissues;Diffraction profiles;Diffraction studies;Molecular signatures;Patient management;Tissue types;Xray imaging