The nature and behavior of chromosome inversions and translocationsare discussed and the literature reviewed. Their uses in cytogeneticand biochemical studies are also outlined and applications are cited.
Linkage data are presented for the genetic positions of sixteentranslocations in chromosomes 9 with reference to the marker genes C,sh1, and wx. Data are also presented for the map positions of fourteentranslocations in chromosome 2, with reference to the genes lg1, gl2,B, sk1, and v4. The uses of duplicate-deficient gametes and pollengrains in cytogenetic investigations are outlined and their applicationsto these studies are described. Techniques for the classification andtransmission of unbalanced chromosome complements are presented and the phenotypic effects of certain gene dosages are described. Availableinformation on each of the thirty translocations mentioned above issummarized and its bearing on previous information regardingchromosomes 2 and 9 is discussed.
Studies are also reported in which the lg1-gl2 and C-wx regionsare moved to different positions in the chromosome complement. Changesof position were brought about by using chromosome rearrangements. Ineach case, the crossover value is measured in the homozygous rearrangementand is compared with the crossover value found when the region isin its standard position. In some cases recombination values fromfemale and male transmission are also compared.
