Biomedical applications of cobalt-spinel ferrite nanoparticles for cancer cell extraction and drug delivery

[摘要] In this presentation it is demonstrated that the unique magnetic properties of superparamagnetic cobalt-spinel ferrite nanoparticles can be employed in several novel applications.A method to selectively capture and remove pathogens from infected organisms to improve longevity is presented.Evidence is provided to show that automated methods using modified forms of hemofiltration or peritoneal dialysis could be used to eliminate the particle/pathogen or particle/infected cell conjugates from the organism postoperatively.It is shown that disparately functionalized nanoparticles can be used in concert as drug carrier and release mechanisms.Lastly, we provide preliminary evidence to support the use of magnetic nanoparticles for controlling reaction kinetics.

[发布机构] University:Georgia Institute of Technology;Department:Chemistry and Biochemistry

[效力级别] Chemiluminescence

[关键词] Nanotechnology;Chemiluminescence;Biochemistry;Peptide;Aptamer;HIV;Drug delivery;Cancer;Magnetic nanoparticles;Nanobiotechnology