Studies on bioactive components from Chinese medicinal plants

[摘要] Several novel bioactive components isolated from Chinese medicinal plants will be presented. These include novel maytansinoid tumor, inhibitors, some new ent-kaurane and rosane diterpenoids from Mallotus anomalus Meer et Chun (Euphorbiaceae), as well asnovel insecticide, stemona alkaloids from Stemona parviflora C. H. Wright (Stemonaceae). Both are native plants of Hainanisland, Chine. 2D NMR techniques such as mono and hetero-COSY, NOESY, COLOC as well as H-NMR line broadening effect were utilized for structure elucidation. The separation techniques, struture elucidations and bioassay results will be reported.

[关键词] Mallotus anomalus;Euphorbiaceae;Stemona parviflora;Stemonoceae;ent-kourane;rosane;delabradane diterpenoids;mayatansinoid;stemona alkaloids;2D NMR techniques