Aplastic crisis due to human parvovirus B19 infection in hereditary hemolytic anaemia

[摘要] Specific anti-B19 IgM was demonstrated in sera from three children showing transient aplastic crisis. A two years-old boy living in Rio de Janeiro suffering from sickle-cell anaemia showed the crisis during August, 1990. Two siblings living in Santa Maria, RS, developed aplastic crisis during May, 1991, when they were also diagnosed for hereditary spherocytosis. For a third child from this same family, who first developed aplastic crisis no IgM anti-B19 was detected in her sera.

[关键词] Human parvovirus B19;Transient aplastic crisis;Hereditary spherocytosis;Sickle-cell disease