The study of chemical composition and pharmacological action of the alkaloid from plants of Lycoris Herb

[摘要] Recently, studies on Lycoris type alkaloids received the attention of scholars home and abroad. Lycoris type contains lots of alkaloids, it can be divided into seven types according to its molecular structure, including Lycorine, Crinine, Galanthamine, Tazettine, Narciclasine, Lycorenine, Homolycorine and Montanine. Researches have shown that Lycoris type possess multiple phamocology activity, such as strong anti-Tumor activity of human breast cancer cell (MCF-7), human leukemia cell(HL-60); and strong inhibition effect of flu virus, measles virus, polio virus and SARS virus; Besides, Lycorine type has strong anti-Acetylcholinesterase effect. In a word, Lycorine type, Lycoris type alkaloids carries multiple pharmacology effect and is a promising substance.

[发布机构] Research Center on Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbin; 150076, China^1;Engineering Research Center of Natural Antineoplastic Drugs, Ministry of Education, Harbin; 150076, China^2

[关键词] Acetylcholinesterase;Anti-tumor activities;Chemical compositions;Human breast cancer cells;Human leukemia cells;Inhibition effect;Measles virus;Pharmacological actions