The potential of pigeon pea (Cajanus cajan) beverage as an anti-diabetic functional drink

[摘要] The number of patients with diabetes continues to increase. Diabetes complications might induce serious diseases such as kidney, nervous, cardiovascular diseases and stroke. Diabetic complications can be prevented by keeping blood glucose and cholesterol at normal levels. This study aims to determine the potential of pigeon pea beverage for lowering glucose and total cholesterol plasma levels and increasing the antioxidant status of diabetic-hypercholesterolemia rats. The research was conducted using 18 Sprague Dawley male rats aged 3 months old with an average body weight of 154 g. The rats were divided into three groups: normal group, D-H group (diabetic-hypercholesterolemia group), and pigeon pea beverage group. The results showed that pigeon pea beverage diet showed hypoglycemic and hypocholesterolemic activities, and could improve the antioxidant status of diabetic-hypercholesterolemia rats. Plasma glucose and total cholesterol levels of diabetic-hypercholesterolemia rats decreased 33.86% and 19.78% respectively. The improvement of the plasma antioxidant status was indicated by the decrease of plasma MDA (malondialdehyde) level, reaching 37.16%. The research result provides an alternative to diabetes management by using the local bean as an anti-diabetic functional drink.

[发布机构] Department of Agricultural Technology, Faculty of Agriculture, Universitas Sebelas Maret, Jl. Ir. Sutami No. 36A, Kentingan, Surakarta; 57126, Indonesia^1;Department of Histology, Faculty of Medicine, Universitas Sebelas Maret, Jl. Ir. Sutami No. 36A, Kentingan, Surakarta; 57126, Indonesia^2

[效力级别] 生物科学

[关键词] Antioxidant status;Cardio-vascular disease;Diabetes management;Hypercholesterolemia;hypocholesterolemic;Hypocholesterolemic activity;hypoglycemic;Pigeon pea