Microwave-Accelerated Iodination of Some Aromatic Amines, Using Urea-Hydrogen Peroxide Addition Compound (UHP) as the Oxidant†

[摘要]

A fast and simple method for the oxidative iodination of some aromatic amines, under microwave irradiation, is reported, using diiodine and the the strongly H-bonded urea-hydrogen peroxide addition compound (H₂NCONH₂···H₂O₂, UHP) as the oxidant. The reactions were carried out in boiling CHCl₃ under a reflux condenser to afford, within 10 minutes, the purified monoiodinated products in 40-80% yields.

[关键词] Monoiodinated arylamines;urea-hydrogen peroxide as oxidant;microwave irradiation