Short Intussusception Valves Prevent Reflux After Jejunal Interposition Bilioduodenal Anastomosis

[摘要] Short whole circumference and semi-circumference intussusception valves were created in interpositioncholecysto-jejunal-duodenal conduits in pigs to determine which method best prevented gastrointestinalreflux into the biliary tract. Following intravenous injection of 99 mTc-HIDA the time interval for itsexcretion from the liver and appearance in the duodenum was not different in either whole or semi-circumferencevalve animals or in controls without valves. After intragastric administration of 99 mTc-DTPA the relative radioactivity of gallbladder contents (reflux) in the cohort without valves wassignificantly higher than in both cohorts with valves. Animals with semi-circumferential valves in turnhad significantly higher levels of nuclide than those with whole circumference valves. Reflux wasobserved grossly in 100% of animals without valves, in 20% of those with semi-circumference valves,and in no animals with whole circumference valves. This study indicates that both Whole and semi-circumferenceintussusception valves placed in jejunal biliary conduits allow unimpeded flow of bile intothe gastrointestinal tract. Whole circumference valves are more effective for prevention of reflux thansemi-circumferential valves.

[学科分类] 过敏症与临床免疫学