Pylorus-Preserving Pancreatoduodenectomy. Experience in 20 Patients

[摘要] Twenty patients underwent a pylorus-preserving pancreatoduodenectomy for benign or malignantperiampullary and pancreatic disease. Eighteen patients had a partial and two patients a totalpancreatectomy. There were 19 elective and 1 emergency operations.Post-operative mortality was 4% (1/20 patients) and the median follow up was 31 months (range, 15–75 months), during which period 8 patients with a malignant disease died.Pylorus-preserving pancreatoduodenectomy did not compromise survival in ampullary cancer.One patient developed a marginal ulcer during the study period and one of twelve patients, examinedby technetium scintigraphy (done more than 3 months after the procedure), had delayed gastricemptying. Two patients presented with a gastric retention as the first sign of recurrent pancreatic cancer.The result of the operation was judged as excellent in 7 patients, good in 8 and as bad in only 2 of the17 patients who survived more than6 months. Body weight was studied in 15 patients surviving morethanone yearafter operation; five patients had gained weight, two had lost weight and in 8 there was nodifference.Pylorus-preserving pancreatoduodenectomy seems to be a valuable alternative in the treatment ofpatients with benign and selected malignant pancreaticobiliary disease.

[学科分类] 过敏症与临床免疫学