Nickel(II) Complexes of Hydrazone ofIsoniazid and Their Magneto-Spectral, Electrochemical,Thermal and Antimicrobial Investigations

[摘要] The synthesis of novel nickel(II) complexes with new ligand derived from hydrazone of isoniazid has been reported. The complexes have general compositions[Ni(L)2X2]or[Ni(L)3](ClO4)2, where L = N-isonicotinamido-furfuraldimine (INH-FFL) andX=Cl−orNCS−. The ligand hydrazone behaves as neutral bidentate (N and O donor) through the carbonyl oxygen and azomethine nitrogen. On the basis of elemental analysis, molecular weight determinations, magnetic susceptibility/moment, thermogravimetric, electrochemical, and spectroscopic studies, the new complexes have been characterized with octahedral geometry. The antibacterial and antifungal studies of the present complexes show that they are moderate antibacterial and antifungal agents.

[学科分类] 无机化学