Intermolecular Interactions between Eosin Y and Caffeine Using1H-NMR Spectroscopy

[摘要] DETECHIP has been used in testing analytes including caffeine, cocaine, and tetrahydrocannabinol (THC) from marijuana, as well as date rape and club drugs such as flunitrazepam, gamma-hydroxybutyric acid (GHB), and methamphetamine. This study investigates the intermolecular interaction between DETECHIP sensor eosin Y (DC1) and the analyte (caffeine) that is responsible for the fluorescence and color changes observed in the actual array. Using1H-NMR,1H-COSY, and1H-DOSY NMR methods, a proton exchange from C-8 of caffeine to eosin Y is proposed.

[学科分类] 光谱学