The Protective Effects ofNigella sativaand Its Constituents on Induced Neurotoxicity

[摘要] Nigella sativa(N. sativa) is an annual plant and widely used as medicinal plant throughout the world. The seeds of the plant have been used traditionally in various disorders and as a spice to ranges of Persian foods.N. sativahas therapeutic effects on tracheal responsiveness (TR) and lung inflammation on induced toxicity by Sulfur mustard.N. sativahas been widely used in treatment of various nervous system disorders such as Alzheimer disease, epilepsy, and neurotoxicity. Most of the therapeutic properties of this plant are due to the presence of some phenolic compounds especially thymoquinone (TQ), which is major bioactive component of the essential oil. The present review is an effort to provide a comprehensive study of the literature on scientific researches of pharmacological activities of the seeds of this plant on induced neurotoxicity.

[学科分类] 药学