The Importance of Definitive Diagnosis in Chronic Schistosomiasis, with Reference toSchistosoma haematobium

[摘要] Schistosomes are long-lived parasites, hence schistosomiasis is a chronic disease with severe long-term implications. However, definitive diagnosis of active infection has been difficult because demonstration of infection has depended on detecting parasite eggs in urine and/or stool. In the case ofSchistosoma haematobiumwhich parasitizes the urinogenital system, this method has low sensitivity in adults. Detection of parasite-specific DNA in urine has been demonstrated and this has similar specificity but improved sensitivity. The implications of this new procedure and the impact on diagnosis are discussed.

[学科分类] 神经科学