Screening and Monitoring Coeliac Disease: Multicentre Trial of a New Serum Antibody Test Kit

[摘要] 99% and 100% respectively, while in patients with other gastrointestinal disorders (disease controls) the specificity was 94% (n=129). The test was also useful in monitoring patients, with anti-gliadin IgA and IgG falling for up to a year after commencing a gluten-free diet (GFD) (12 adults). In some patients however, antibody levels did not reach the normal cutpoint after many months on a GFD, which may reflect the patients ' poor adherence to their gluten free diet. The test was superior to the Pharmacia anti-gliadin ELISA, and should be useful as an aid to the diagnosis of coeliac disease, as well as in the follow-up of treated patients.

[学科分类] 生理学与病理学