Chronic myelogenous leukemia after postoperative adjuvant S-1 therapy for rectal cancer: a case report

[摘要] We report a case in which chronic myelogenous leukemia (CML) developed after postoperative adjuvant S-1 therapy for rectal cancer. A 56-year-old man was diagnosed with rectal adenocarcinoma, which was treated with abdominoperineal resection followed by a year of adjuvant S-1 therapy. At 39 postoperative months, he was diagnosed with CML. Although it remains unclear that CML that develops after treatment involving cytotoxic agents is treatment-related, clinicians should be aware of the possibility of CML developing after S-1 therapy.

[学科分类] 血液学

[关键词] Chronic myelogenous leukemia;rectal cancer;fluoropyrimidine;S-1