Phytochemical Composition and Antioxidant Potential ofRuta graveolensL.In VitroCulture Lines

[摘要] Ruta graveolensL. is a medicinal plant used in traditional systems of medicine for treatment of psoriasis, vitiligo, leucoderma, and lymphomas with well-known anti-inflammatory and anticancer properties. Therefore antioxidant potential ofR. graveolens(in plantaandin vitro) was investigated. As antioxidants present in plant extracts are multifunctional, their activity and mechanism depends on the composition and conditions of the test system. Therefore, the total antioxidant capacity was evaluated using assays that detect different antioxidants: free radical scavenging (DPPH and ABTS), transition metal ion reduction (phosphomolybdenum assay), reducing power, and nitric oxide reduction. Content of furanocoumarin-bergapten in the extracts showed good corelation with free radical scavenging, transition metal reduction and reducing power,while total phenolic content showed good corelation with nitric oxide reduction potential. Antioxidant activity ofin vitrocultures was significantly higher compared toin vivoplant material. The present study is the first report on comprehensive study of antioxidant activity ofR. graveolensand itsin vitrocultures.

[学科分类] 植物学