Fibronectin Adsorption to Nanopatterned Silicon Surfaces

[摘要] The possibility of using surface topography for guidance of different biological molecules and cells is a relevant topic that can be applied to a wide research activity. This study investigated the adsorption of fibronectin to adiffraction grated silicon surface. The rectangular grating profile featured acontrolled surface with 350 nm period and a corrugation depth of 90 nm. Results demonstrated that the controlled surface had asignificantly positive effect on the fibronectin binding. Thus, nanoscalesurface topography can enhance fibronectin binding.

[学科分类] 材料工程