Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications

[摘要] Aging, chronic inflammation, and environmental insults play an important role in a number of disease processes through alterations of the epigenome. In this review we explore how age-related changes in the epigenetic landscape can affect heterogeneity within the haematopoietic stem cell (HSC) compartment and the deriving clinical implications.

[学科分类] 生物技术