General Analytical Procedure for Determination of Acidity Parameters of Weak Acids and Bases

[摘要] The paper presents a new convenient, inexpensive, and reagent-saving general methodology for the determination ofpKavalues for components of the mixture of diverse chemical classes weak organic acids and bases in water solution, without the need to separate individual analytes. The data obtained from simple pH-metric microtitrations are numerically processed into reliablepKavalues for each component of the mixture. Excellent agreement has been obtained between the determinedpKavalues and the reference literature data for compounds studied.

[学科分类] 分析化学