Palladium(II) Complexes ContainingMixed Nitrogen-Sulphur Donor Ligands: Interaction of [Pd(Methionine Methyl Ester)(H2O)2]2+with Biorelevant Ligands

[摘要] Pd(MME)Cl2complex (MME = methionine methyl ester) was synthesised and characterized by physicochemical measurements.The reaction of [Pd(MME)(H2O)2]2+with amino acids, peptides, or dicarboxylic acids was investigated at 25°C and 0.1 M ionic strength. Amino acids and dicarboxylic acids form 1 : 1 complexes. Peptides form both 1 : 1 complexes and the corresponding deprotonated amide species. Thestability of the complexes formed was determined and the binding centres of the ligands were assigned. Effect of solvent on the stability constant of Pd(MME)-CBDCA complex, taken as a representative example, shows that the complex is more favoured in a medium of low dielectric constant. The concentration distribution diagrams of the complexes were evaluated.

[学科分类] 物理化学和理论化学