Clinical Manifestations, Treatment,and Outcome of Hospitalized Patients withPlasmodium vivaxMalaria in Two Indian States: A Retrospective Study

[摘要] This was a retrospective study done on 110 patients hospitalized withP. vivaxmalariainthree medical college hospitals, one in the union territory of Chandigarh and the other two in Gujarat, that is, Ahmedabad and Surat. The clinical presentation, treatment, and outcome were recorded. As per WHO criteria for severity, 19 of 110 patients had severe disease—six patients had clinical jaundice with hepatic dysfunction, three patients had severe anemia, three had spontaneous bleeding, two had acute respiratory distress syndrome, and one had cerebral malaria, hyperparasitemia, renal failure, circulatory collapse, and metabolic acidosis. All patients with severeP. vivaxmalaria survived, but one child with cerebral malaria had neurological sequelae. There was wide variation in the antimalarial treatment received at the three centres.Plasmodium vivaxmalaria can no longer be considered a benign condition. WHO guidelines for treatment ofP. vivaxmalaria need to be reinforced.

[学科分类] 传染病学