Effects on Metabolic Health after a 1-Year-Lifestyle Intervention in Overweight and Obese Children: A Randomized Controlled Trial

[摘要] Objective.To evaluate the effect of a family-based intervention on anthropometric andmetabolic markers in overweight and obese children.Methods.Overweight or obese 8–12 years olds (n= 93) were randomized into intervention orcontrol groups. The intervention group participated in a program aiming for lifestyle changesregarding food habits and physical activity. Anthropometric measures and venous bloodsamples were collected from all children at baseline and after 1 year.Results.BMI z-scores decreased in both groups, 0.22 (P= 0.002) and 0.23 (P= 0.003) in intervention and control group, respectively, during the 1-year study, but there was no difference in BMI between the groups at 1-year measurement (P= 0.338). After 1 year, there was a significant difference in waist circumference, waist/hip ratio, and apolipoprotein B/A1 ratio between intervention and control group.Conclusions.The intervention had limited effects on anthropometrics and metabolic markers, which emphasizes the need of preventing childhood overweight and obesity.

[学科分类] 内分泌与代谢学