Comparison of Venous Thromboembolism after Total Hip Arthroplasty between Ankylosing Spondylitis and Osteoarthritis

[摘要] Objective.Ankylosing spondylitis (AS), an inflammatory rheumatic disease, will gradually lead to severe hip joint dysfunction. Total hip arthroplasty is a useful method to improve patients’ quality of life. The aim of this study was to compare the incidence and risk factors of deep vein thrombosis (DVT) between AS and hip osteoarthritis.Methods.In a retrospective study, a total of 149 subjects who underwent cementless THA were studied. Clinical data, biochemical data, and surgery-related data were measured between AS and OA groups.Results.The incidence of DVT in AS group was lower than that of OA group, although no significant difference was detected (P=0.89). The patients of AS group were much younger (P<0.0001) and thinner (P=0.018) compared with those of OA group. AS patients had higher ejection fraction (EF) (P=0.016), higher platelet counts (P<0.0001), and lower hypertension rate (P=0.0004). The values of APTT, PT, and INR in AS patients were higher than those in OA patients (allP<0.0001). The values of D-dimer and APTT were both significantly higher in DVT subjects than those in non-DVT subjects.Conclusion.AS patients potentially had a lower incidence of DVT compared with OA patients.

[学科分类] 基础医学