Diagnosis of High-Grade Osteosarcoma by Radiology and Cytology: A Retrospective Study of 52 Cases

[摘要] The diagnostic value of combined radiology and fine needle aspiration cytology (FNAC) was retrospectively assessed ina consecutive series of 52 patients with high-grade osteosarcoma. The series was divided into typical and atypicalosteosarcomas according to radiological features and site. Thirty-two of 33 radiologically typical osteosarcoma cases werecorrectly diagnosed by cytology; one lesion was diagnosed as sarcoma NOS. Nineteen osteosarcoma cases wereradiographically atypical. Six of these were diagnosed as osteosarcoma and another six as sarcoma NOS. In three casesanother type of sarcoma was suggested. One case was falsely classified as benign. FNAC of three cases were non-diagnostic.Overall, the diagnostic difficulties pertained to the radiologically atypical cases. Notably, four of these also posedconsiderable difficulties in the histopathological assessment prompting external consultation. Our study suggests that openbiopsy can be obviated in high-grade osteosarcomas exhibiting typical radiological features, i.e., in two-thirds.

[学科分类] 肿瘤学