Malignant Hemangiopericytoma Arising in Neurofibromatosis: A CaseReport with Histological, Immunohistochemical and UltrastructuralStudies

[摘要] Subject.A 27-year-old Hispanic male with clinical manifestation ofneurofibromatosis type 1 developed chronic constipation and urination difficulty along withrecently increased abdominal bloating and anorexia. He also noted 40 lbs weight loss over period of 1 year. Physical and radiographic examinations revealed a large mass in the right pelvic fossa.Results.The surgically removed tumor was demonstrated, histologically, immunohistochemically, and ultrastructurally, to be a malignant hemangiopericytoma.Discussion.Although non-neurogenic tumors associated with neurofibromatosishave been reported in these patients, only one hemangiopericytoma case has been found in the English literature. We report here another case of this rare malignanthemangiopericytoma in a patient with neurofibromatosis.

[学科分类] 肿瘤学