A Guideline for the Management of Gastrointestinal StromalTumour (GIST)

[摘要] Gastrointestinal stromal tumour (GIST) is the commonest mesenchymal tumour to affect the gastrointestinal tract.Appropriate management requires accurate diagnosis and the skills of a multidisciplinary team. Surgery is the only curativetreatment option and should be performed whenever feasible, by experienced personnel. For patients with advancedunresectable or metastatic disease, the receptor tyrosine kinase inhibitor imatinib offers effective therapy and can provideeffective palliation for the majority of patients with this disease. The background to this recent development and aguideline for the management of GIST is proposed.

[学科分类] 肿瘤学