Salivary Glucose Concentration and Excretion in Normal and Diabetic Subjects

[摘要] The present report aims mainly at a reevaluation of salivary glucose concentration and excretion in unstimulated and mechanically stimulated saliva in both normal and diabetic subjects. In normal subjects, a decrease in saliva glucose concentration, an increase in salivary flow, but an unchanged glucose excretion rate were recorded when comparing stimulated saliva to unstimulated saliva. In diabetic patients, an increase in salivary flow with unchangedsalivary glucose concentration and glucose excretion rate were observed under the sameexperimental conditions. Salivary glucose concentration and excretion were much higher indiabetic patients than in control subjects, whether in unstimulated or stimulated saliva. Nosignificant correlation between glycemia and either glucose concentration or glucoseexcretion rate was found in the diabetic patients, whether in unstimulated or stimulated saliva.In the latter patients, as compared to control subjects, the relative magnitude of the increase insaliva glucose concentration was comparable, however, to that of blood glucoseconcentration. The relationship between these two variables was also documented in normalsubjects and diabetic patients undergoing an oral glucose tolerance test.

[学科分类] 基础医学