Sugammadex and Ideal Body Weight in Bariatric Surgery

[摘要] Background. The obese patients have differences in body composition, drug distribution, and metabolism. Sugammadex atT2recovery in a dose of 2 mg kg−1of real body weight (RBW) can completely reverse the NMB block; in our study we investigated the safety and efficacy of Sugammadex dose based on their ideal body weight (IBW).Methods. 40 patients ofboth sexes undergoing laparoscopic bariatric surgery were enrolleddivided into 2 groups according to the dose of Sugammadex: the first received a dose of 2 mg kg−1of IBW and the second received a dose of 2 mg kg−1of RBW. Both were anesthetized with doses calculated according to the IBW:fentanyl 2 μg kg−1, propofol 3 mg kg−1, rocuronium0,6 mg kg−1, oxygen, air, and desflurane (6–8%). Maintenance doses of rocuronium were 1/4 of the intubation dose. Sugammadex was administrated atT2recovery.Results. The durations of intubation and maintenance doses of rocuronium were similar in both groups.In IBW group, theT4/T1value of 0.9 was reached in 151 ± 44 seconds and in 121 ± 55 seconds in RBW group (P=0.07).Discussion. Recovery times toT4/T1of 0.9 are surprisingly similar in both groups without observing any postoperative residual curarization.Conclusion. Sugammadex doses calculated according to the IBW are certainly safe for a rapid recovery and absence of PORC.

[学科分类] 外科医学