Towards properly controlled analyticalmeasurement methods

[摘要] It is of great practical importance to develop simple methods for theautomatic detection ofthe controlled state of the analytical methodbeing applied. The key point is to find quantities that greatly affectthe quality of the analytical results and that can be easily estimatedduring the measurement process from the measured data. Thesignal-to-noise ratio has proved to be such a quantity in gaschromatographic methods. The statistical properties of theestimation of the signal-to-noise ratio from gas chromatographicdata have been investigated. The suggested practical method forestimating the signal-to-noise ratio proved to be biased from amathematical statistical point of view, but the bias is usually notgreater than 10%. It has been shown by practical examples that thesignal-to-noise ratio affects the quality of the analytical results andit is easy to estimate its value from practical data.

[学科分类] 分析化学